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Coralan, Servier Uses & Indications
Symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm, who have a contraindication or intolerance for beta-blockers.
For the different doses, film-coated tablets containing 5 mg and 7.5 mg ivabradine are available.
The usual recommended starting dose of ivabradine is 5 mg twice daily. After three to four weeks of treatment, the dose may be increased to 7.5 mg twice daily depending on the therapeutic response.
If, during treatment, heart rate decreases persistently below 50 beats per minute (bpm) at rest or the patient experiences symptoms related to bradycardia such as dizziness, fatigue or hypotension, the dose must be titrated downward including the possible dose of 2.5 mg twice daily (one half 5 mg tablet twice daily). Treatment must be discontinued if heart rate below 50 bpm or symptoms of bradycardia persist.
| Coralan, Servier Side Effects |
| AV 1st degree block (ECG prolonged PQ interval) |
| Bradycardia |
| Dizziness |
| Eye disorders |
| Headache |
| Luminous phenomena (phosphenes) |
Coralan, Servier Side Effects
Luminous phenomena (phosphenes) were reported by 14.5% of patients, described as a transient enhanced brightness in a limited area of the visual field. They are usually triggered by sudden variations in light intensity. The onset of phosphenes is generally within the first two months of treatment after which they may occur repeatedly. Phosphenes were generally reported to be of mild to moderate intensity. All phosphenes resolved during or after treatment, of which a majority (77.5%) resolved during treatment. Fewer than 1% of patients changed their daily routine or discontinued the treatment in relation with phosphenes.
Bradycardia was reported by 3.3% of patients particularly within the first 2 to 3 months of treatment initiation. 0.5% of patients experienced a severe bradycardia below or equal to 40 bpm.
Your long-term vision could be at risk if you suffer from Glaucoma and leave it untreated. Glaucoma is a condition that causes fluid in the eye to build up. It happens because the fluid is unable to fully drain. When the fluid builds up it puts pressure on the optic nerve which slowly damages the optic nerve and causes long-term vision loss. Glaucoma symptoms are often slight and go un-noticed, especially at the beginning so as you age it is important to go for regular eye checks.
If you start experiencing a loss of peripheral vision, get it checked out immediately. this is one of the most common symptoms of Glaucoma. Using medication eye drops is normally enough to control the degeneration of the optic nerve and there are a few different choices of eye drops to decide upon.
Customer Reviews for Coralan, Servier
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